[
    {
        "id": 1,
        "titulo": "Potential bioactive compounds of medicinal plants against new Coronavirus (SARS-CoV-2): A review",
        "descripcion": "Nowadays, COVID-19 cases are growing worldwide, and there is no evidence of an effective drug to combat the new SARS-CoV-2 virus.",
        "reporte": "Nowadays, COVID-19 cases are growing worldwide, and there is no evidence of an effective drug to combat the new SARS-CoV-2 virus. In this sense, medicinal plants as an alternative treatment are being used without control to handle the pandemic situation. Therefore, bioactive compounds against Coronavirus of medicinal plant species that grow in Ecuador are discussed. The plant species described in this review are <i>Azadirachta indica, Cinchona pubescens, Coriandrum sativum, C\u00farcuma longa, Eucalyptus spp, Morus alba, and Salvia rosmarinus<\/i>[A3]; and compunds are curcumin, coriandrin, deoxynojirimycin, kuwanon G, mulberroside A, oleanolic acid, rosmarinic acid, ursolic acid, quinine, eucalyptol, and jensenone.",
        "imagen": "assets\/images\/reportes-investigacion\/Reporte_0.png"
    },
    {
        "id": 2,
        "titulo": "Effect of solvent-solvent partition on antioxidant activity and GC-MS profile of Ilex guayusa Loes. Leaves extract and fractions",
        "descripcion": "The use of guayusa (<i>Ilex guayusa Loes.<\/i>) leaves as functional food has increase recently. This work discusses the antioxidant activity and volatile compounds of guayusa leaves extract and fractions.",
        "reporte": "The use of guayusa (<i>Ilex guayusa Loes.<\/i>) leaves as functional food has increase recently. This work discusses the antioxidant activity and volatile compounds of guayusa leaves extract and fractions. The methanol crude extract was obtained by maceration, subsequently hexane, chloroform, ethyl acetate, and aqueous fractions were collected by solvent-solvent partition. Total phenolic content (TPC), total flavonol\/flavone content (TFC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, and ferric reducing antioxidant power (FRAP) were measured by ultraviolet-visible (UV-Vis) spectrophotometry. This bioactivity could be related to phenolic acids, flavones and flavonols content, as well as the caffeine, dodecanoic acid isopropyl ester, caffeic acid, and malic acid identified by gas chromatography-mass spectrometry (GC-MS). These findings support the antioxidant properties of this plant material.",
        "imagen": "assets\/images\/reportes-investigacion\/Reporte_1.png"
    },
    {
        "id": 3,
        "titulo": "Bioprospecci\u00f3n de plantas y productos naturales con potencial antiviral frente a varios tipos de coronavirus: Una revisi\u00f3n bibliogr\u00e1fica de especies localizadas en territorio ecuatoriano",
        "descripcion": "El Coronavirus-disease-2019 (COVID-19) es una enfermedad causada por el virus SARS-CoV-2, que ha provocado una pandemia. Es potencialmente mortal para la poblaci\u00f3n m\u00e1s vulnerable, torn\u00e1ndose un desaf\u00edo para el Ecuador y en especial para Guayaquil, dada la gran escasez de recursos hospitalarios y de medicina para los pacientes.",
        "reporte": "El Coronavirus-disease-2019 (COVID-19) es una enfermedad causada por el virus SARS-CoV-2, que ha provocado una pandemia. Es potencialmente mortal para la poblaci\u00f3n m\u00e1s vulnerable, torn\u00e1ndose un desaf\u00edo para el Ecuador y en especial para Guayaquil, dada la gran escasez de recursos hospitalarios y de medicina para los pacientes. El objetivo de este trabajo fue elaborar una base de datos sobre plantas medicinales, alimentos funcionales y productos naturales mediante la revisi\u00f3n de art\u00edculos cient\u00edficos con resultados exitosos sobre inhibir varios tipos de coronavirus y su respectiva correlaci\u00f3n con los mismos productos localizados en Ecuador. El resultado de esta b\u00fasqueda fue la construcci\u00f3n de un cuadro recopilatorio de plantas medicinales y alimentos funcionales cuyas propiedades puedan contribuir a reducir los s\u00edntomas que provocan los coronavirus en general, el mismo que desestabiliza el Sistema Renina-Angiotensina (SRA) provocando diferentes patolog\u00edas. Lo cual sugiere el posible uso ben\u00e9fico de los Inhibidores de la Enzima Convertidora de Angiotensina (IECA) y los Bloqueadores del Receptor de Angiotensina II (BRAs) de origen natural frente al COVID-19. La informaci\u00f3n aqu\u00ed descrita servir\u00e1 para futuras investigaciones en \u00e1reas de la medicina y la farmac\u00e9utica, fomentar las buenas pr\u00e1cticas de bioprospecci\u00f3n, para asegurar los intereses de los pueblos ancestrales de los pa\u00edses en desarrollo localizadas.",
        "imagen": "assets\/images\/reportes-investigacion\/Reporte_2.png"
    },
    {
        "id": 4,
        "titulo": "Anti-inflammatory and sedative activities of Peperomia galioides: in vivo studies in mice",
        "descripcion": "Aerial parts (leaves, flowers, stem) of <i>Peperomia galioides<\/i> extract administered to mice, was used to confirm its anti-inflammatory and sedative folk uses.",
        "reporte": "Aerial parts (leaves, flowers, stem) of <i>Peperomia galioides<\/i> extract administered to mice, was used to confirm its anti-inflammatory and sedative folk uses. The anti-inflammatory activity was assessed by croton oil-induced ear oedema and myeloperoxidase (acute inflammation); cotton pellet-induced granuloma (sub-acute inflammation) and Escherichia coli Lipopolysaccharide (LPS) induced inflammation (cellular mediators). The sedative activity was studied by the pentobarbital-induced sleeping time test. Single doses (300 and 600 mg\/kg; i.p.) of the extract reduced croton oil-induced ear oedema and myeloperoxidase activity. Six days administration of the extract (300 mg\/kg, i.p.) to mice implanted with cotton pellets diminished granuloma formation. LPS (20 mg\/kg, i.p.) enhanced plasma nitrites and TNF-\u03b1 levels that were inhibited by the extract. The duration but not the onset of sleeping time was enhanced by 300 and 600 mg\/kg of the extract. Our results show that <i>P. galioides<\/i> has anti-inflammatory and sedative activities in mice, which validates its traditional use.",
        "imagen": "assets\/images\/reportes-investigacion\/Reporte_3.png"
    }
]